History of science credits the Flemish physician, alchemist and philosopher Jan Baptist Van Helmont (1579-1644) for his contributions to the development of chemistry and medicine. Yet, as this book makes clear, focussing on Van Helmont's impact on modern science does not do justice to the complexity of his thought or to his influence on successive generations of intellectuals like Robert Boyle or Gottfried Leibniz. Revealing Van Helmont as an original thinker who sought to produce a post-Scholastic synthesis of religion and natural philosophy, Georgiana Hedesan reconstructs his ambitious quest for universal knowledge as it emerges from the text of the Ortus medicinae (1648). Published after Van Helmont's death by his son, the work can best be understood as a compilation of finished and unfinished treatises, the historical product of a life unsettled by religious persecution and personal misfortune. The present book provides a coherent account of Van Helmont's philosophy by analysing